張俊哲教授簡介 (About Dr. Chun-che Chang)

Vasa,

germline development, 

and Me

(請點選上述關鍵字)

Boss of the Lab

(請點選上述關鍵字)

實驗室主持人: 張俊哲老師

學歷：

1996-2001 博士 (Ph.D.)，英國劍橋大學遺傳系 (Department of Genetics and Wellcome/CRC Institute, University of Cambridge) (Supervisor: Professor Michael Akam, FRS)

1990-1992 碩士，國立臺灣大學生化科學研究所

1987-1990 學士，國立臺灣大學農化系農製組 (現國立臺灣大學生化科技學系)

1986-1987 學士，國立臺灣大學植病系昆蟲組 (現國立臺灣大學生昆蟲學系)

(小學: 炎峰國小; 初中: 懷恩中學 (現東大附中); 高中: 台中一中)

經歷與服務：

張俊哲教授簡介：在國立臺灣大學農化系農製組 (現為生化科技系)、理學院生化科學研究所畢業後，公費留考赴英國劍橋大學遺傳系取得博士學位。 2003 年 8 月受聘教於臺大昆蟲學系 (助理教授, 2003-2009; 副教授, 2009-2014; 教授, 2014-迄今)，亦為臺大生物科技研究所、基因體與系統生物學學位學程等單位合聘教師。張老師專長為發育生物學與分子遺傳學，「分子生物學」是他在臺大的主授課，2007 年迄今曾 7 度獲得校級教學優良之榮譽 (2007, 2010, 2011, 2012, 2013, 2014, 2015)。在研究方面，曾榮獲臺大生農學院年輕學者學術研究獎與學術獎勵，亦曾擔任國科會/科技部初、複審委員。除了專業課程，張老師還開授「新生專題」與相關科普課程，並擔任臺大教學發展中心電子報主編，是位很樂於分享與幫助同學的科學家。詳細資訊請參考其個人網頁 (lgdntu.blogspot.com/)。(摘自 “3 小時讀通 DNA 誕生之謎")

開授課程：

1. 分子生物學 (主授; 從 2009 年 9 月開始)

2. 遺傳學 (合開)

3. 科學研究計畫管理 - 科學之路 (主授)

4. DNA 與發育多樣性 (主授)

5. 當代生殖細胞發育主題研討 (主授; 從 2003 年 9 月開始)

6. 昆蟲生物技術 (主授)

7. 基礎昆蟲學 (合開)

8. 生物技術專題研究 (主授)

9. 整合生物學專題講座 (合開)

10. 現代科技與人類文明 (合開)

11. 工程與專業倫理 (合開)

12. 服務 (一)、(二)

13. 專題研究 (主授)

14. 學士論文

15. 碩士論文

16. 博士論文

17. 新生專題 (Freshmen Seminar; 從 2009 年 9 月開始) (主授)

18. 分子遺傳 (Molecular Genetics; 合開; 從 2010 年 2 月開始) (合開)
19. 進階科學研究計畫管理 (主授; 從 2013 年 2 月開始)

張俊哲老師團隊之研究成果

研究成果刊登於期刊封面

* 通訊作者

+ 等同貢獻

Chung C.Y., Cook C.E., Lin G.W., Huang T.Y., and Chang, C-c.* (2013) Reliable protocols for whole-mount fluorescent in situ hybridization (FISH) in the pea aphid Acyrthosiphon pisum: a comprehensive survey and analysis. Insect Science (in press)

Hsiao, Y. M., Lin, G.W., and Chang, C-c.* (2013) Establishment of the pea aphid as a developmental model

organism: history, significance, and future prospects. Formosan Entomologist (in press)

Chang, C-c.†*,  Hsiao, Y. M.†,  Huang, T. Y., Cook, C. E., Shigenobu, S.; Chang, T. H. (2013) Noncanonical expression of caudal during early embryogenesis in the pea aphid Acyrthosiphon pisum: maternal cad-driven posterior development is not conserved.  Insect Molecular Biology, 22: 442–455. doi: 10.1111/imb.12035 (SCI；2014 年雜誌封面)




Lu, H. L., Tanguy, S., Rispe, C., Gauthier, J., Walsh, T., Gordon, K., Edwards, O., Tagu, D., Chang, C-c.*, Jaubert-Possamai, S.* (2011) Expansion of Genes Encoding piRNA-Associated Argonaute Proteins in the Pea Aphid: Diversification of Expression Profiles in Different Plastic Morphs. PLoS ONE 6(12): e28051. doi:10.1371/journal.pone.0028051 (* co-corresponding authors)

科學影像刊登於期刊封面

Yi-Chung Chen, Bo-Kai Wu, Cheng-Ying Chu, Chia-Hsiung Cheng, Hau-Wei Han, Gen-Der Chen, Ming-Ting Lee, Pung-Pung Hwang, Koichi Kawakami, Chun-Che Chang, and Chang-Jen Huang* (2010) Identification and characterization of alternative promoters of zebrafish Rtn-4/Nogo genes in cultured cells and zebrafish embryos. Nucleic Acids Research 38:4635-4650. (SCI)

The International Aphid Genomics Consortium (2010) Genome Sequence of the Pea Aphid Acyrthosiphon pisum. PLoS Biology 8(2): e1000313. doi:10.1371/journal.pbio.1000313. (Chun-che Chang is designated as a leader of the germline gene annotation group in the paper; Cover story; cover image of this issue is contributed by the Chang Lab) (SCI)



Ting-Yu Huang, Charles E. Cook, Gregory K. Davis, Shuji Shigenobu, Rita P.-Y. Chen, and Chun-che Chang* (2010) Anterior development in the parthenogenetic and viviparous form of the pea aphid, Acyrthosiphon pisum: hunchback and orthodenticle expression. Insect Molecular Biology 19: 75-85. (SCI)



Shuji Shigenobu*, R. D. Bickel, J. A. Brisson, T. Butts, C.-c. Chang et al. (2010) Comprehensive survey of developmental genes in the pea aphid, Acyrthosiphon pisum: frequent lineage-specific duplications and losses of developmental genes. Insect Molecular Biology 19: 47-62.

Yi-Chun Tsai, Leellen F. Solter, Chih-Yuan Wang, Huai-Sheng Fan, Chun-che Chang*, Chung-Hsiung Wang* (2009) Morphological and molecular studies of a microsporidium (Nosema sp.) isolated from the three spot grass yellow butterfly, Eurema blanda arsakia (Lepidoptera: Pieridae). Journal of Invertebrate Pathology 100: 85-93. (SCI)

Chun-che Chang*, Ting-Yu Huang, Charles E. Cook, Gee-Way Lin, Chun-Liang Shih, and Rita P.-Y. Chen (2009) Developmental expression of Apnanos during oogenesis and embryogenesis in the parthenogenetic pea aphid Acyrthosiphon pisum (Hemiptera: Aphidoidea). International Journal of Developmental Biology 53: 169-176. (SCI)

Taro Mito, Taro Nakamura, Isao Sarashina, Chun-che Chang, Shotaro Ogawa, Hideyo Ohuchi, and Sumihare Noji (2008) Dynamic expression patterns of vasa during embryogenesisin the cricket Gryllus bimaculatus. Development Genes Evolution 218: 381-387. (SCI)

Chun-che Chang*, Ting-Yu Huang†, Chun-Liang Shih, Gee-Way Lin, Te-Pin Chang, Hui Chiu, Wen-Chang Chang (2008) Whole-mount identification of gene transcripts in aphids: Protocols and evaluation of probe accessibility. Archives of Insect Biochemistry and Physiology 68: 186-96. (SCI)

Chun-che Chang*, Hui Chiu, and How-Jing Lee (2008) Identification of nuage-like structures in the panoistic ovarioles of the German cockroach Blattella germanica (Linnaeus). Formosan Entomologist 28: 1-10. (Cover story)

Gee-Way Lin, Shau-Lin Lu, Ting-Yu Huang, Chun-Liang Shih, Wen-Jer Wu*, and Chun-che Chang* (2008) Molecular identification of weevils significant for customs inspection and quarantine importance. Formosan Entomologist 28: 43-55. (This paper was written in Chinese)

Chun-che Chang*, Gee-way Lin, Charles E. Cook, Shwu-bin Horng, How-jing Lee and Ting-yu Huang (2007) Apvasa marks germ-cell migration in the parthenogenetic pea aphid Acyrthosiphon pisum (Hemiptera: Aphidoidea). Development Genes Evolution 217: 275–287 (SCI)

Chun-che Chang*, Wen-chih Lee, Charles E. Cook, Gee-way Lin, and Tschining Chang (2006) Germ-plasm specification and germline development in the parthenogenetic pea aphid Acyrthosiphon pisum: Vasa and Nanos as markers. International Journal of Developmental Biology 50: 413-421. (Cover story

; cited by Cell (2006) and PNAS (2007)) (SCI)

 (2003 年以前的發表)

Chun-che Chang, Peter Dearden, and Michael Akam* (2002) Germline development in the grasshopper Schistocerca gregaria: Vasa as a marker. Developmental Biology 252: 110-118. (SCI) (Cover story)

Chun-che Chang and Charles E. Cook* (2002) Trends in genomic “evo-devo". 3 (7): reports 4019.1-4019.2. Genome Biology. (peer-reviewed) (SCI)